There are two ways to initiate treatment with ARISTADA: Refer to the prescribing information of oral aripiprazole for the recommended dosage and administration of the oral formulation. Due to the half-life of oral aripiprazole, it may take up to 2 weeks to fully assess tolerability. For patients who have never taken aripiprazole, establish tolerability with oral aripiprazole prior to initiating treatment with ARISTADA. DOSAGE AND ADMINISTRATION Recommended DosageĪRISTADA is only to be administered as an intramuscular injection by a healthcare professional. The inactive ingredients include sorbitan monolaurate (3.8 mg/mL), polysorbate 20 (1.5 mg/mL), sodium chloride (6.1 mg/mL), sodium phosphate dibasic anhydrous, sodium phosphate monobasic and water for injection.ĪRISTADA is indicated for the treatment of schizophrenia in adults. The chemical structure is:ĪRISTADA is available as a white to off-white sterile aqueous extended-release suspension for intramuscular injection in the following strengths of aripiprazole lauroxil (and deliverable volumes from a single-use pre-filled syringe): 441 mg (1.6 mL), 662 mg (2.4 mL), 882 mg (3.2 mL) and 1064 mg (3.9 mL). The empirical formula is C 36H 51C l2N 3O 4 and its molecular weight is 660.7 g/mol. The chemical name of aripiprazole lauroxil is 7-2-oxo-3,4-dihydro-2H-quinolin-1-yl)methyl dodecanoate. DESCRIPTIONĪRISTADA contains aripiprazole lauroxil, an atypical antipsychotic. ARISTADA is not approved for the treatment of patients with dementia-related psychosis. INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSISĮlderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.
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